All News from ProteoToul
![MetaboHUB and ProFI Joint Day](https://proteotoul.ipbs.fr/wp-content/uploads/2024/02/metabohub_profi-300x163.png)
MetaboHUB and ProFI Joint Day
The MetaboHUB and ProFI national infrastructures are organizing a joint day in Toulouse on Tuesday, March 26, 2024. During the...
![Workshop on Quantitative Proteomics 2024](https://proteotoul.ipbs.fr/wp-content/uploads/2024/02/sete-300x151.jpg)
Workshop on Quantitative Proteomics 2024
ProFI organizes a new edition of the CNRS workshop (Ecole Thématique, held in French) in quantitative proteomics with a focus...
![Welcome to ProFI’s new nodes !](https://proteotoul.ipbs.fr/wp-content/uploads/2023/11/carto_new_profi-300x153.png)
Welcome to ProFI’s new nodes !
Following the final decision of our Institutional Committee on September 20th 2023, we are delighted to announce that three new...
![timsTOF SCP mass spectrometer installed at ProteoToul](https://proteotoul.ipbs.fr/wp-content/uploads/2023/03/vignette_timstof-300x289.png)
timsTOF SCP mass spectrometer installed at ProteoToul
Thanks to the REACT-EU OCSSIGEN projet (Région Occitanie, FEDER funds), ProteoToul has acquired a high sensitivity timsTOF SCP mass spectrometer...
![Carole Pichereaux : l’expertise en protéomique](https://proteotoul.ipbs.fr/wp-content/uploads/2022/10/portrait_fraib-300x169.jpg)
Carole Pichereaux : l’expertise en protéomique
En 2023, il y aura 20 ans que Carole Pichereaux exerce à la Fédération ses talents de protéomicienne. Ce néologisme...
![MaxQuant Summer School](https://proteotoul.ipbs.fr/wp-content/uploads/2022/10/maxquant_summer_school-300x225.jpg)
MaxQuant Summer School
At the beginning of September the 13th International Summer School on Computational Mass Spectrometry-Based Proteomics was held in Barcelona. Two...
![Understanding how T lymphocytes discriminate between antigens of varying affinities](https://proteotoul.ipbs.fr/wp-content/uploads/2022/11/ot-i_paper_1-300x300.jpg)
Understanding how T lymphocytes discriminate between antigens of varying affinities
T lymphocytes are essential cells of the immune system, and have the ability to sense a wide range of antigenic...
![Julien Marcoux’s HDR](https://proteotoul.ipbs.fr/wp-content/uploads/2022/10/julien_marcoux.jpg)
Julien Marcoux’s HDR
Structural Mass Spectrometry of membrane proteins and large protein complexes Building on his expertise acquired around the concept of Structural...
![Pascaline Bories’s PhD defensis](https://proteotoul.ipbs.fr/wp-content/uploads/2022/09/these_pascaline-300x254.png)
Pascaline Bories’s PhD defensis
In cellulo targeting of protein-protein interactions within Mycobacterium tuberculosis FAS-II complex: an innovating approach for new TB drugs Responsible for...
![The spermatoproteasome: a key enzymatic complex in spermatogenesis](https://proteotoul.ipbs.fr/wp-content/uploads/2022/04/spermatoproteasome-300x212.jpg)
The spermatoproteasome: a key enzymatic complex in spermatogenesis
The spermatoproteasome is found exclusively in mammalian germ cells and is essential for spermatogenesis. It differs from the constitutive proteasome...
![Deciphering the proximal TCR signaling network in mice and humans](https://proteotoul.ipbs.fr/wp-content/uploads/2022/03/tcr_signaling_network-300x198.png)
Deciphering the proximal TCR signaling network in mice and humans
T lymphocytes are essential cells of the immune system, that specifically recognize a wide range of pathogens, but also malignant...
![Refeyn Mass Photometer Acquisition](https://proteotoul.ipbs.fr/wp-content/uploads/2022/03/refeyn_mass_photometer-300x225.png)
Refeyn Mass Photometer Acquisition
We recently acquired a mass photometer from Refeyn Ltd. to measure the molecular weight (MW) of single protein and protein...
![HDX-MS describes different catalytic conformations of an ABC transporter involved in multidrug resistance](https://proteotoul.ipbs.fr/wp-content/uploads/2022/03/hdx-ms_2022-02-29-300x160.png)
HDX-MS describes different catalytic conformations of an ABC transporter involved in multidrug resistance
The emergence of antibiotic resistant “superbugs” is a real threat for our society and ATP Binding Cassette (ABC) transporters is...
![Julien Marcoux is awarded a grant from the France-Arizona Institute for Global Grand Challenges](https://proteotoul.ipbs.fr/wp-content/uploads/2022/03/lysis-300x222.png)
Julien Marcoux is awarded a grant from the France-Arizona Institute for Global Grand Challenges
Pore-forming peptides are natural and highly effective molecular weapons used by a wide range of organisms, including human cells (A),...
![Analyses protéomiques quantitatives : Choix de méthodes et analyses des données](https://proteotoul.ipbs.fr/wp-content/uploads/2022/03/ecole_thematique_cnrs_2022-300x208.jpg)
Analyses protéomiques quantitatives : Choix de méthodes et analyses des données
Annonce de l’ouverture des inscriptions pour la prochaine école thématique du CNRS sur le thème des analyses protéomiques quantitatives avec...
![Conformational maps of human 20S proteasomes reveal PA28- and immuno-dependent inter-ring crosstalks](https://proteotoul.ipbs.fr/wp-content/uploads/2021/01/hdx-ms-nature-comm-300x199.png)
Conformational maps of human 20S proteasomes reveal PA28- and immuno-dependent inter-ring crosstalks
HDX-MS—based study of the differences between the conformational dynamics of standard and i20s reveals specific, allosteric changes in i20S and...
![Intramolecular dialogue within the human proteasome](https://proteotoul.ipbs.fr/wp-content/uploads/2021/01/3d-structure-standard-human-proteasome-e1610546446746-300x241.png)
Intramolecular dialogue within the human proteasome
The proteasome is a proteolytic machinery allowing the recycling of intracellular proteins. Its deregulation has been associated with various neurodegenerative...
![Inserm Workshop 262: Mass Spectrometry for Structural Biology](https://proteotoul.ipbs.fr/wp-content/uploads/2020/12/Inserm-workshop-262-300x239.png)
Inserm Workshop 262: Mass Spectrometry for Structural Biology
This workshop will present the fundamental and applied aspects of Mass Spectrometry-based structural techniques, as well as data analysis procedures....
![Proline: an efficient and user-friendly software suite for large-scale proteomics](https://proteotoul.ipbs.fr/wp-content/uploads/2020/12/proline-publication-300x200.jpg)
Proline: an efficient and user-friendly software suite for large-scale proteomics
We are pleased and very proud to announce the publication of Proline in Bioinformatics. Motivation The proteomics field requires the...
![HDX-Viewer: interactive 3D visualization of hydrogen-deuterium exchange data](https://proteotoul.ipbs.fr/wp-content/uploads/2020/12/hdx-viewer-300x234.png)
HDX-Viewer: interactive 3D visualization of hydrogen-deuterium exchange data
Bouyssié D, Lesne J, Locard-Paulet M, Albigot R, Burlet-Schiltz O, Marcoux J. Bioinformatics. 2019 Jul 9. pii: btz550. doi: 10.1093/bioinformatics/btz550....