All News from ProteoToul

Carole Pichereaux : l’expertise en protéomique

Carole Pichereaux : l’expertise en protéomique

En 2023, il y aura 20 ans que Carole Pichereaux exerce à la Fédération ses talents de protéomicienne. Ce néologisme...

by Renaud Albigot28/10/2022
MaxQuant Summer School

MaxQuant Summer School

At the beginning of September the 13th International Summer School on Computational Mass Spectrometry-Based Proteomics was held in Barcelona. Two...

by Renaud Albigot27/10/2022
Understanding how T lymphocytes discriminate between antigens of varying affinities

Understanding how T lymphocytes discriminate between antigens of varying affinities

T lymphocytes are essential cells of the immune system, and have the ability to sense a wide range of antigenic...

by Renaud Albigot26/10/2022
Julien Marcoux’s HDR

Julien Marcoux’s HDR

Structural Mass Spectrometry of membrane proteins and large protein complexes Building on his expertise acquired around the concept of Structural...

by Renaud Albigot20/10/2022
Pascaline Bories’s PhD defensis

Pascaline Bories’s PhD defensis

In cellulo targeting of protein-protein interactions within Mycobacterium tuberculosis FAS-II complex: an innovating approach for new TB drugs Responsible for...

by Renaud Albigot27/09/2022
The spermatoproteasome: a key enzymatic complex in spermatogenesis

The spermatoproteasome: a key enzymatic complex in spermatogenesis

The spermatoproteasome is found exclusively in mammalian germ cells and is essential for spermatogenesis. It differs from the constitutive proteasome...

by Renaud Albigot06/04/2022
Deciphering the proximal TCR signaling network in mice and humans

Deciphering the proximal TCR signaling network in mice and humans

T lymphocytes are essential cells of the immune system, that specifically recognize a wide range of pathogens, but also malignant...

by Renaud Albigot30/03/2022
Refeyn Mass Photometer Acquisition

Refeyn Mass Photometer Acquisition

We recently acquired a mass photometer from Refeyn Ltd. to measure the molecular weight (MW) of single protein and protein...

by Renaud Albigot30/03/2022
HDX-MS describes different catalytic conformations of an ABC transporter involved in multidrug resistance

HDX-MS describes different catalytic conformations of an ABC transporter involved in multidrug resistance

The emergence of antibiotic resistant “superbugs” is a real threat for our society and ATP Binding Cassette (ABC) transporters is...

by Renaud Albigot29/03/2022
Julien Marcoux is awarded a grant from the France-Arizona Institute for Global Grand Challenges

Julien Marcoux is awarded a grant from the France-Arizona Institute for Global Grand Challenges

Pore-forming peptides are natural and highly effective molecular weapons used by a wide range of organisms, including human cells (A),...

by Renaud Albigot16/03/2022
Analyses protéomiques quantitatives : Choix de méthodes et analyses des données

Analyses protéomiques quantitatives : Choix de méthodes et analyses des données

Annonce de l’ouverture des inscriptions pour la prochaine école thématique du CNRS sur le thème des analyses protéomiques quantitatives avec...

by Renaud Albigot16/03/2022
Conformational maps of human 20S proteasomes reveal PA28- and immuno-dependent inter-ring crosstalks

Conformational maps of human 20S proteasomes reveal PA28- and immuno-dependent inter-ring crosstalks

HDX-MS—based study of the differences between the conformational dynamics of standard and i20s reveals specific, allosteric changes in i20S and...

by Julien Marcoux17/01/2021
Intramolecular dialogue within the human proteasome

Intramolecular dialogue within the human proteasome

The proteasome is a proteolytic machinery allowing the recycling of intracellular proteins. Its deregulation has been associated with various neurodegenerative...

by Renaud Albigot04/01/2021
Inserm Workshop 262: Mass Spectrometry for Structural Biology

Inserm Workshop 262: Mass Spectrometry for Structural Biology

This workshop will present the fundamental and applied aspects of Mass Spectrometry-based structural techniques, as well as data analysis procedures....

by Renaud Albigot29/12/2020
Proline: an efficient and user-friendly software suite for large-scale proteomics

Proline: an efficient and user-friendly software suite for large-scale proteomics

We are pleased and very proud to announce the publication of Proline in Bioinformatics.   Motivation The proteomics field requires the...

by Renaud Albigot23/12/2020
HDX-Viewer: interactive 3D visualization of hydrogen-deuterium exchange data

HDX-Viewer: interactive 3D visualization of hydrogen-deuterium exchange data

Bouyssié D, Lesne J, Locard-Paulet M, Albigot R, Burlet-Schiltz O, Marcoux J. Bioinformatics. 2019 Jul 9. pii: btz550. doi: 10.1093/bioinformatics/btz550....

by Renaud Albigot23/12/2020