Structural Mass Spectrometry encompasses an extending range of methods aiming at collecting as much structural information on a biomolecule as possible, including :
- Native MS and Ion Mobility-MS,
- Hydrogen-Deuterium Exchange,
- Top-Down Proteomics,
- Cross-linking.
Native MS and Ion Mobility-MS
Stoichiometry Non-cov. binding
HDX-MS
Solvent accessibility Dynamics / Allosteric change
Top-Down Proteomics
Proteoforms PTMs, truncations…