LymphoAtlas: a dynamic and integrated phosphoproteomic resource to study the activation of immune cells

  • Mining of the T cell phosphoproteome at a depth of 13,000 unique phosphorylated peptides and around 7,000 phosphorylation sites with fast‐sequencing MS
  • Time-resolved map of phosphoregulations during the first 10 min after TCR stimulation of primary T cells
  • Identification of novel effectors involved in the TCR signaling pathway
  • A web application to facilitate the exploration of the LymphoAtlas database by the scientific community https://bmm-lab.github.io/LymphoAtlas
References

Locard-Paulet, M et al. LymphoAtlas: A Dynamic and Integrated Phosphoproteomic Resource of TCR Signaling in Primary T Cells Reveals ITSN2 as a Regulator of Effector Functions. Mol. Syst. Biol. 2020, 16 (7), e9524. https://doi.org/10.15252/msb.20209524.