Structural Mass Spectrometry of Protein Assemblies

Often reduced to the analysis of the primary structure of proteins, Mass Spectrometry has evolved over the past 20 years to provide information on the secondary, tertiary and even quaternary structure of proteins.

Characterization of Inflammatory and Immune Processes

Taking advantage of the great improvements in large-scale proteomic analysis of complex samples, we use state-of-the-art mass spectrometry techniques to study the molecular mechanisms of the inflammatory and immune responses in specific cellular systems, such as endothelial cells and different types of immune cells.

Discovery of Biomarkers

High-resolution mass spectrometry-based proteomics and label-free quantitative methods have progressed tremendously in recent years, and became increasingly popular as an attractive and powerful way to analyse differential protein expression in complex biological samples, particularly in the field of biomarker discovery.

Data management and proteomics tools development

Proteomics data analysis requires the use of dedicated computer hardware to acquire and store data and tools to validate, quantify and classify proteins. The Toulouse Proteomics Infrastructure has gained over the years an important expertise in bioinformatics with specialized staff to handle data storage, data processing, and data analysis and also to develop new pipelines […]